| First Author | Park SY | Year | 2005 |
| Journal | Genesis | Volume | 43 |
| Issue | 2 | Pages | 80-6 |
| PubMed ID | 16108006 | Mgi Jnum | J:155851 |
| Mgi Id | MGI:4417826 | Doi | 10.1002/gene.20157 |
| Citation | Park SY, et al. (2005) Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene. Genesis 43(2):80-6 |
| abstractText | We generated transgenic mice expressing firefly (Photinus pyralis) luciferase (luc) under the control of the mouse insulin I promoter (MIP). The mice have normal glucose tolerance and pancreatic islet architecture. The luciferase-expressing beta cells can be readily visualized in living mice using whole-body bioluminescent imaging. The MIP-luc transgenic mice may be useful for monitoring changes in beta cell function or mass in living animals with normal or altered metabolic states. |
