Primary Identifier | MGI:4415616 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Hes7-cre)1Kag |
Strain of Origin | Not Specified | Is Recombinase | true |
Is Wild Type | false |
molecularNote | Nuclear localizing Cre recombinase is expressed under control of a 5.4-kb genomic DNA fragment containing the Hes7 (hairy and enhancer of split 7 (Drosophila)) promoter. Cre mRNA is expressed in the presomitic mesoderm (PSM) of the E10.5 embryo, and its expression appears to oscillate. In doubly transgenic embryos bearing this transgene and a lacZ reporter transgene, X-gal staining is observed throughout the PSM and in the somites and their derivatives at E7.5-E10.5. |