Primary Identifier | MGI:4418563 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Ehmt1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 23 was floxed and an FRT-flanked neo cassette was inserted into intron 23 via homologous recombination. The selection cassette was then removed by flp mediated recombination. Cre-mediated recombination results in out-of-frame splicing and nonsense mediated decay of the mutant transcript. |