| Primary Identifier | MGI:4418756 | Allele Type | Targeted |
| Attribute String | Reporter | Gene | Cyp19a1 |
| Transmission | Germline | Strain of Origin | 129S/SvEv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | This allele contains an internal ribosome entry site (IRES), a human placental alkaline phosphatase gene, a second IRES, and a nuclear-targeted E. coli nlacZ gene inserted three base pairs 3' of the stop codon of the aromatase gene. The targeting vector also contained a self-excising neomycin resistance cassette (ACN) upstream of the IRES-ALPP-IRES nlacZ. Upon passage through the male germline ACN was deleted, leaving a single loxP site and the IRES-ALPP-IRES-nlacZ construct. |
