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Allele : Phox2b<tm4Jbr> paired-like homeobox 2b; targeted mutation 4, Jean-Francois Brunet
Primary Identifier  MGI:4418298 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Phox2b
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site and FRT flanked neo cassette were inserted upstream of exon 3 and a loxP site and mutated exon 3 containing a 7 alanine expansion of a 20-residue polyalanine chain were inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Phox2b<27Alacki>,
  • Phox2b<27Alacki>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories





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