| Primary Identifier | MGI:4418710 | Organism | mouse, laboratory |
| Chromosome | UN | Mgi Type | heritable phenotypic marker |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Used to study neurodegeneration with brain iron accumulation 2a. PHENOTYPE: As early as 3 weeks of age homozygotes show signs of sensory axonopathy (clasping reflex and ataxia) which progress to paraparesis and morbidity by 6 months of age. Large swollen axons (spheroids) are noted in the brainstem and spinal cord. Males fail tobreed, likely due to hindlimb muscle atrophy. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
