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Allele : Rec114<tm1(KOMP)Wtsi> REC114 meiotic recombination protein; targeted mutation 1, Wellcome Trust Sanger Institute

Primary Identifier  MGI:4419253 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Rec114
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
description  Cell line EPD0392_4_D08 was successfully used to make chimeric mice. Germline transmission was accomplished. J:271216
molecularNote  The insertion of the L1L2_Bact_P cassette created a deletion of size 5762 starting at position 58567450 and ending at position 58573212 of Chromosome 9 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Rec114<->,
  • 2410076I21Rik<tm1(KOMP)Wtsi>,
  • Rec114<->,
  • 2410076I21Rik<tm1(KOMP)Wtsi>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories