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Allele : Tg(tetO-SNCA)1Cai transgene insertion 1, Huaibin Cai

Primary Identifier	MGI:4420977	Allele Type	Transgenic
Attribute String	Humanized sequence, Inducible, Inserted expressed sequence	Gene	Tg(tetO-SNCA)1Cai
Strain of Origin	C57BL/6	Induced With	doxycycline/tetracycline
Is Recombinase	false	Is Wild Type	false

molecularNote

A transgenic vector was generated encoding the human SNCA gene under the control of a tetO promoter. The construct was microinjected into fertilized oocytes, and a line of mice was established.

mutations:
Insertion

synonyms:
alpha-syn WT,
alpha-syn WT

earliestPublication:
Lin X, et al. (2009) Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein. Neuron 64(6):807-27

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

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