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Allele : Acan<tm1(cre/ERT2)Crm> aggrecan; targeted mutation 1, Benoit de Crombrugghe
Primary Identifier  MGI:4420223 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Acan
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  IRES-cre/ERT2 and an FRT-flanked PGK-neo selection cassette (in reverse orientation to the target gene) was inserted into the 3' UTR of the Aggrecan gene by homologous recombination in G4 ES cells. The line was established by breeding to C57BL/6 mice. The neo cassette was not removed.
  • mutations:
  • Insertion
  • synonyms:
  • Agc1<tm(IRES-creERT2)>,
  • Agc1<CreERT2),
  • Agc<tm(IRES-CreERT-Neo-pgk>,
  • Agc1<tm(IRES-creERT2)>,
  • Agc<tm(IRES-CreERT-Neo-pgk>,
  • Agc<Cre>,
  • Agc1<CreERT2),
  • Agc<Cre>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

75 Publication categories





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