| Primary Identifier | MGI:4421140 | Allele Type | Targeted |
| Gene | Naca | Transmission | Germline |
| Strain of Origin | 129/Sv | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 4 was replaced with a modified exon 4 with a T to G mutation that results in an amino acid of alanine for serine at position 43 (S43A). A floxed neo cassette used for ES cell selection was removed by cre mediated recombination. In vitro, the mutation prevents phosphorylation at position 43 and subsequently reduce translocation into the nucleus. |
