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Allele : Ptgs2<tm1.1Wls> prostaglandin-endoperoxide synthase 2; targeted mutation 1.1, William L Smith

Primary Identifier  MGI:4420987 Allele Type  Targeted
Gene  Ptgs2 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Genomic sequence that codes for amino acids 595 through 612 was deleted by mutagenesis. A floxed neo cassette was inserted upstream of the modified exon 10. Cre mediated recombination removed the neo cassette. The predicted protein lacks the last 18 C-terminal amino acids.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • delta 18 muCox2,
  • delta 18 muCox2
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories