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Allele : Ewsr1<tm2(FLI1*)Sblee> Ewing sarcoma breakpoint region 1; targeted mutation 2, Sean Lee

Primary Identifier  MGI:4429147 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence, Null/knockout Gene  Ewsr1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP-flanked transcriptional stop signal in the antisense direction was inserted into intron 6. Exon 7 was fused to exons 5-9 of human FLI1 with a C-terminal FLAG tag, and a 3' neo cassette, replacing exons 8 through 11 by homologous recombination. The absence of endogenous protein product was confirmed by western blot analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ews/FL1<Stop>,
  • EF<Stop>,
  • EF<Stop>,
  • Ews/FL1<Stop>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories