Primary Identifier | MGI:4420758 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inducible, Inserted expressed sequence | Gene | Tg(tetO-LRRK2)C7874Cai |
Strain of Origin | C57BL/6J | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A transgenic vector was generated encoding the C-terminal hemagglutinin (HA)-tagged human LRRK2 gene under the control of a tetO promoter. The construct was microinjected into C57BL/6J fertilized oocytes, and 5 independent lines were generated including line C7874. Founder mice were bred to C57BL/6J mice to establish this colony. |