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Allele : Myd88<tm1.1Defr> myeloid differentiation primary response gene 88; targeted mutation 1.1, Anthony L DeFranco

Primary Identifier	MGI:4421295	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Myd88
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

Mice carrying the Myd88^tm1Defr allele were crossed with Tg(Zp3-cre)93Knw mice to remove exon 3.

mutations:
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Hou B, et al. (2008) Toll-like Receptors Activate Innate and Adaptive Immunity by using Dendritic Cell-Intrinsic and -Extrinsic Mechanisms. Immunity 29(2):272-82

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

3 Carried By

0 Driven By

326 Publication categories

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