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Allele : Tg(tetO-Ppargc1a)1Dpk transgene insertion 1, Daniel P Kelly

Primary Identifier	MGI:4429485	Allele Type	Transgenic
Attribute String	Inducible, Inserted expressed sequence	Gene	Tg(tetO-Ppargc1a)1Dpk
Strain of Origin	FVB	Induced With	doxycycline/tetracycline
Is Recombinase	false	Is Wild Type	false

molecularNote

Mouse Ppargc1a (peroxisome proliferative activated receptor, gamma, coactivator 1 alpha) cDNA with a C-terminal myc-his tag was placed under the control of the tetracycline operator (tetO).

mutations:
Insertion

synonyms:
TRE-PGC-1 alpha,
TRE-PGC-1 alpha

earliestPublication:
Russell LK, et al. (2004) Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner. Circ Res 94(4):525-33

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

14 Publication categories

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