| Primary Identifier | MGI:4429702 | Allele Type | Targeted |
| Attribute String | Recombinase | Gene | Rfx6 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | Recombineering methods were used to modify a BAC containing the Rfx6 gene and generate the targeting construct. Homologous recombination in ES cells resulted in the first 5 exons being replaced by and EFGP/cre fusion gene followed by an FRT-flanked neo cassette. The neo was subsequently removed by crossing mice carrying the disrupted allele with Actb-Flp mice. |
