| Primary Identifier | MGI:4430191 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Dnase1l1 |
| Inheritance Mode | Recessive | Transmission | Germline |
| Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A neomycin resistance cassette has replaced a segment of the gene including exons 3-5; exon 3 contains the ATG translation initiation codon. If splicing occurs between exons 2 and 6, translation from the only in-frame ATG would yield a 60-amino acid (aa) peptide (the full length protein contains 302 aa) that lacks the activity domain. |
