Primary Identifier | MGI:4431035 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Abpa-cre)1Cmal |
Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The transgene construct contained a 3.4 kb fragment of the cre recombinase sequence dowstream of the 1.5 kb rat Abpa promoter. This was followed by the metallothionein I (MT-1) sequence with polyA signal. The purified, linearized construct was injected into fertilized B6D2F1 oocytes. 10 founders were obtained, with 9 showing testicular cre mRNA expression. One line was propagated. |