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Publication : Data on metabolic profile of insulin-degrading enzyme knockout mice.

First Author  Borges DO Year  2019
Journal  Data Brief Volume  25
Pages  104023 PubMed ID  31198829
Mgi Jnum  J:339471 Mgi Id  MGI:7522584
Doi  10.1016/j.dib.2019.104023 Citation  Borges DO, et al. (2019) Data on metabolic profile of insulin-degrading enzyme knockout mice. Data Brief 25:104023
abstractText  Insulin-degrading enzyme (IDE) degrades and inactivates bioactive peptides such as insulin. As insulin is a master regulator of glucose homeostasis, lack of IDE is expected to have a profound impact on both insulin and glucose levels. This article shares data on glucose and insulin homeostasis of control, heterozygous and knockout mice for Ide after 18 weeks of a normal chow diet. This data article is related to a research article entitled "Knockout of insulin-degrading enzyme leads to mice testicular morphological changes and impaired sperm quality" (Meneses et al., 2019).
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