First Author | Borges DO | Year | 2019 |
Journal | Data Brief | Volume | 25 |
Pages | 104023 | PubMed ID | 31198829 |
Mgi Jnum | J:339471 | Mgi Id | MGI:7522584 |
Doi | 10.1016/j.dib.2019.104023 | Citation | Borges DO, et al. (2019) Data on metabolic profile of insulin-degrading enzyme knockout mice. Data Brief 25:104023 |
abstractText | Insulin-degrading enzyme (IDE) degrades and inactivates bioactive peptides such as insulin. As insulin is a master regulator of glucose homeostasis, lack of IDE is expected to have a profound impact on both insulin and glucose levels. This article shares data on glucose and insulin homeostasis of control, heterozygous and knockout mice for Ide after 18 weeks of a normal chow diet. This data article is related to a research article entitled "Knockout of insulin-degrading enzyme leads to mice testicular morphological changes and impaired sperm quality" (Meneses et al., 2019). |