| Primary Identifier | MGI:4434827 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Plvap |
| Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | EUCOMM |
| description | Cell line HEPD0550_4_E12 was successfully used to make chimeric mice. Germline transmission was accomplished. J:203907 |
| molecularNote | The L1L2_Bact_P cassette was inserted at position 71961688 of Chromosome 8 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml |
