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Allele : Maged1<tm1.1Urfm> MAGE family member D1; targeted mutation 1.1, Olivier De Backer

Primary Identifier	MGI:4437118	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Maged1
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 4-12 were floxed, and a floxed neo cassette was placed within intron 3 by homologous recombination. The neo cassette and floxed exons have been removed. Immunoblotting of brain lysates demonstrated that full-length protein was absent in homozygous animals.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Bertrand MJ, et al. (2008) NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo. Cell Death Differ 15(12):1921-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

10 Publication categories

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