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Allele : Dkkl1<tm1.1Mldp> dickkopf-like 1; targeted mutation 1.1, Melvin DePamphilis

Primary Identifier  MGI:4438465 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dkkl1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert loxP sites flanking exons 2-4 of the Dickkopf-Like 1 (Dkkl1) gene, and a frt-flanked neomycin resistance (neo) cassette upstream of the 3' loxP site. Cre mediated recombination removed exons 2 through 4 and the frt-flanked neo cassette. The absence of protein expression was confirmed by immunohistochemistry on testis samples.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele