| Primary Identifier | MGI:4438465 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Dkkl1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector was designed to insert loxP sites flanking exons 2-4 of the Dickkopf-Like 1 (Dkkl1) gene, and a frt-flanked neomycin resistance (neo) cassette upstream of the 3' loxP site. Cre mediated recombination removed exons 2 through 4 and the frt-flanked neo cassette. The absence of protein expression was confirmed by immunohistochemistry on testis samples. |