| Primary Identifier | MGI:4436759 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Foxp3 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The complete EGFP coding sequence was inserted in-frame in the first coding exon followed immediately by a cassette containing three stop codons. This same stop codon cassette was also inserted in exon 5 near its 5' end. An FRT site flanked neomycin resistance gene cassette was inserted 246 bp 5' of exon 1 as well. Chimeric mice were subsequently mated to an flp-deleter strain to excise the neo selection cassette. The full length endogenous protein is not expressed. |
