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Allele : Gnb1<Gt(prvSStrap)4B8Yiw> guanine nucleotide binding protein (G protein), beta 1; gene trap 4B8, Yoichiro Iwakura

Primary Identifier  MGI:4438390 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Gnb1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A gene trap vector, containing the splice acceptor site, beta-gal, and hygromycin phosphotransferase gene (hygR), was randomly inserted into the first intron of the gene, creating the 4B8 mutant ES cell line. RT-PCR analyses indicated that RNA transcripts were not detected in E10.5 mutant embryos. Western blot analysis showed that the protein was absent in mutant retina.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Gbeta1<->,
  • Gbeta1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

7 Publication categories