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Allele : Mrgprd<tm4.1(COP4)Mjz> MAS-related GPR, member D; targeted mutation 4.1, Mark J Zylka

Primary Identifier  MGI:4439026 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Mrgprd
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The genomic region coding for amino acids 2 through 315 of 321 amino acids was replaced with an inframe human cDNA with the nucleotide substitution resulting in the amino acid substitution of arginine for histidine at position 134 (H134R) fused to Venus and followed by a floxed self-excising neo cassette. Expression of the fusion protein in nonpeptidergic neurons was confirmed by immunohistochemistry.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Mrgprd-ChR2-Venus,
  • Mrgprddelta<hChR2(H134R)Venus>,
  • Mrgprddelta<hChR2(H134R)Venus>,
  • Mrgprd-ChR2-Venus
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele