Primary Identifier | MGI:4439515 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lgi1 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Cre mediated recombination removed exons 3 through 8 of a MICER clone with a K14-Agouti gene, 3'Hprt, loxP site, and puro cassette inserted downstream of a duplicated exons 1 and 2 and a neo cassette, loxP site, 5'Hprt, and tyrosinase gene inserted downstream of exon 8. The absence of transcript expression was confirmed by RT-PCR analysis on hippocampus and cortex extracts. |