| Primary Identifier | MGI:4440642 | Allele Type | Spontaneous |
| Gene | Scrib | Inheritance Mode | Recessive |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | ENU mutagenesis induced a C-to-T transition at coding nucleotide 4522 (ENSMUST00000002603) in exon 33. This mutation results in a nonsense mutation of arginine 1508 truncating the protein by 158 amino acids (p.R1508*). A 65% reduction in transcript expression was confirmed by qRT-PCR. |
