Primary Identifier | MGI:4441277 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Sp2 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129P2/OlaHsd)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Two loxP sites were inserted to flank exon 3 of the gene, followed by an SA-IRES-lacZ-neo-SVpA cassette and a third loxP site after the cassette in intron 3. Northern blot analyses revealed aberrant mRNA expression. Immunoblot analysis showed the absence of the full-length protein; a truncated N-terminal fragment was below the detection limit. |