| Primary Identifier | MGI:4441286 | Allele Type | Targeted |
| Attribute String | Conditional ready, Hypomorph, No functional change | Gene | Tie1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 1 and an frt flanked neo cassette with a 5' loxP site was inserted downstream of exon 1. Western blot analysis confirmed a 76% reduction in protein expression in the lungs of E18.5 homozygous mice. This is a hypomorphic allele. |
