Primary Identifier | MGI:4441771 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Prdm14 |
Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
Is Recombinase | false | Is Wild Type | false |
Project Collection | EUCOMM |
description | Cell line EPD0525_5_H11 was successfully used to make chimeric mice. Germline transmission was accomplished. J:200019 |
molecularNote | The L1L2_gt0 cassette was inserted at position 13194009 of Chromosome 1 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml |