| Primary Identifier | MGI:4442462 | Allele Type | Targeted |
| Attribute String | Conditional ready, Modified regulatory region, No functional change | Gene | Pax3 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 674 bp neural crest enhancer region within the upstream genomic region was replaced by a flowed PGK-neo cassette. Immunohistochemistry showed a drastic reduction or complete loss of protein expression in homozygous embryos at E12.5. Removal of the PGK-neo cassette with Cre-expressing mice allows for tissue-specific rescue. |
