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Allele : Pex7<tm1Nbra> peroxisomal biogenesis factor 7; targeted mutation 1, Nancy Braverman

Primary Identifier  MGI:4443125 Allele Type  Targeted
Attribute String  Hypomorph Gene  Pex7
Transmission  Germline Strain of Origin  129S/SvEv
Is Recombinase  false Is Wild Type  false
molecularNote  A neo cassette was inserted within intron 2 in the reverse orientation. Use of cryptic splice sites within the cassette reduces the amount of wild-type transcript produced. Quantitative RT-PCR analysis detected very low levels of wild-type transcript in brain, liver, kidney, and lung from homozygous mice; thus, this is a hypomorpic allele.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Pex7<neo>,
  • Pex7<neo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories