Primary Identifier | MGI:4443125 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Pex7 |
Transmission | Germline | Strain of Origin | 129S/SvEv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neo cassette was inserted within intron 2 in the reverse orientation. Use of cryptic splice sites within the cassette reduces the amount of wild-type transcript produced. Quantitative RT-PCR analysis detected very low levels of wild-type transcript in brain, liver, kidney, and lung from homozygous mice; thus, this is a hypomorpic allele. |