| Primary Identifier | MGI:4450977 | Allele Type | Targeted |
| Gene | Clps | Transmission | Germline |
| Strain of Origin | 129X1/SvJ | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The 15 base pairs in exon 1 encoding enterostatin, a pentapeptide (APGPR) produced from cleavage of the pro-colipase peptide, were removed. A floxed neo cassette was also inserted into intron 1 and subsequently removed by cre mediated recombination. Normal expression of a slightly smaller colipase protein was confirmed by western blot analysis on pancreas extracts. Enzymatic assay confirmed normal colipase activity. |
