| Primary Identifier | MGI:4442238 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Chd6 |
| Transmission | Germline | Strain of Origin | 129S1/SvImJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A floxed and FRT flanked neomycin cassette was inserted 5' to exon 12 and third loxP site inserted 3' to exon 12. The selection cassette and exon 12 were removed by cre mediated recombination. This deletion removes 81 amino acids of the SWI2/SNF2-like domain which encodes motif I, a key ATP-binding motif, and motif Ia, which has DNA-binding activity. The modified protein is produced at wild type levels. |
