Primary Identifier | MGI:4442602 | Allele Type | Chemically induced (ENU) |
Gene | Pax2 | Inheritance Mode | Dominant |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | ENU mutagenesis induced an A to G transition at position 220 (no source sequence accession number provided) resulting in the amino acid subsitution of alanine for threonine at position 74 (T74A). Reduced steady-state protein levels were confirmed by western blot analysis on embryo extracts. |