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Allele : Ikbkb<tm2.1Mka> inhibitor of kappaB kinase beta; targeted mutation 2.1, Michael Karin

Primary Identifier  MGI:4453210 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ikbkb
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
description  ES cell line = GS (Genome Systems).
molecularNote  The floxed exon 3 in Ikbkbtm2Mka was removed via cre-mediated recombination by breeding with Tg(Vil-cre)1Mka mice. Although this cre transgene is expressed in the small intestinal epithelial and colon epithelial cells, a small amount of cre recombination occurred in the testis resulting in germline transmission of the exon 3 deleted allele.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • IKKbeta<delta>,
  • IKKbeta<delta>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories