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Allele : Cdkn1b<tm1Wcl> cyclin dependent kinase inhibitor 1B; targeted mutation 1, Warren C Ladiges

Primary Identifier  MGI:4455327 Allele Type  Targeted
Gene  Cdkn1b Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  The gene was modified by insertion of a loxP-flanked neomycin resistance cassette in intron 2 and replacement of T by G at nucleotide position 326, in exon 1, resulting in substitution of glycine for valine at amino acid position 109 of the protein (V109G), a variation that may be associated with progression of some human cancers.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • P27V109G,
  • p27<V109G>,
  • P27 V109G Knock-in,
  • P27V109G,
  • p27<V109G>,
  • Cdkn1b<1800Wcl>,
  • Cdkn1b<1800Wcl>,
  • P27 V109G Knock-in
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories