| Primary Identifier | MGI:4458032 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Pold1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A point mutation resulting in an aspartic acid to alanine substition at residue 400 (D400A) was introduced at the endogenous locus by homologous recombination of a targeting vector also carrying an intronic neo cassette. The neo cassette was removed by cre-mediated recombination. The missense mutation was introduced into sequence encoding the proofreading domain. |