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Allele : Braf<tm1Rima> Braf transforming gene; targeted mutation 1, Richard Marais
Primary Identifier  MGI:4458346 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Braf
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 15 was replaced with one containing nucleotide substitutions that result in the amino acid substitution of alanine for aspartic acid at position 594 (D594). The modified exon 15 is preceded by a loxP site, a cDNA encoding exons 15 through 18, a termination sequence, and a floxed neo cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Braf<LSL-D594A>,
  • LSL-Braf<D594A>,
  • Braf<LSL-D594A>,
  • LSL-Braf<D594A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories





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