Primary Identifier | MGI:4459468 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Dot1l |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Cre mediated recombination removed exon 5, exon 6, and the beta-geo cassette. The predicted protein product is expected to lack several conserved motifs in the Dot1L catalytic domain, including the SAM-binding motif and motifs X, I, and II. |