| Primary Identifier | MGI:4459519 | Allele Type | Targeted |
| Gene | Clcn7 | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Nucleotide substitutions result in the amino acid substitution of alanine for glutamic acid at position 245 (E245A). This mutation is predicted to uncouple the chloride ion conduction from the proton exchanger function. An frt flanked neo cassette inserted upstream of exon 8 was removed by flp mediated recombination. |
