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Allele : Tg(LRRK2)WT1Mjfa transgene insertion WT1, Matthew Farrer

Primary Identifier  MGI:4460657 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(LRRK2)WT1Mjfa
Strain of Origin  FVB/NTac Is Recombinase  false
Is Wild Type  false
molecularNote  These transgenic mice express the human LRRK2 gene with high levels of protein detected, with an expression pattern similar to that of endogenous mouse Lrrk2. The transgene inserted into Chromosome 12. Transgenic mice express human LRRK2 approximately 20-22 fold over the endogenous mouse Lrrk2 level. Line WT1 was generated.
  • mutations:
  • Insertion
  • synonyms:
  • LRRK2 WT,
  • hWT,
  • LRRK2 WT,
  • hWT
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

9 Publication categories