| Help | About | Contact Us

Allele : Fgfr2<m1Sgg> fibroblast growth factor receptor 2; mutation 1, S G Gong

Primary Identifier	MGI:4461798	Allele Type	Chemically induced (ENU)
Gene	Fgfr2	Inheritance Mode	Not Specified
Strain of Origin	C3H/HeJ	Is Recombinase	false
Is Wild Type	false

molecularNote

ENU mutagenesis induced nucleotide substitutions in exon 7 that result in the amino acid substitution of arginine for tryptophan at position 290 (W290R). This mutation is predicted to disrupt FGFR2 IIIb and IIIc isoforms.

mutations:
Nucleotide substitutions

synonyms:
Fgfr2<W290R>,
Fgfr2<W290R>

earliestPublication:
Mai S, et al. (2010) The missense mutation W290R in Fgfr2 causes developmental defects from aberrant IIIb and IIIc signaling. Dev Dyn 239(6):1888-900

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=75879368

MouseMine