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Allele : Hoxb8<tm4.1(cre/Esr1*)Mrc> homeobox B8; targeted mutation 4.1, Mario R Capecchi

Primary Identifier  MGI:4818431 Allele Type  Targeted
Attribute String  Recombinase Gene  Hoxb8
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  true Is Wild Type  false
molecularNote  Exon 1 of Hoxb8 was replaced with cre fused to a mutated estrogen receptor followed by an FRT-flanked neo selection cassette. The neo was subsequently removed by breeding to FLPe deleter animals. In homozygous mice, the allele acts as a null allele for Hoxb8.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Hoxb8-CreER<TM>,
  • Hoxb8-CreER<TM>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

4 Publication categories

Trail: Allele