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Allele : Tg(Thy1-PSEN1*G384A)45Jckr transgene insertion 45, Mathias Jucker

Primary Identifier  MGI:4819105 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Thy1-PSEN1*G384A)45Jckr
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A human PSEN1 cDNA with a mutation in the codon for amino acid residue 384 causing a glycine to alanine change (G384A) was placed under the control of the murine Thy1.2 minigene. This mutant form is known to increase Abeta1-42 production.
  • mutations:
  • Insertion
  • synonyms:
  • PS45,
  • PS45
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

23 Publication categories