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Allele : Trp53<tm1.1Dgj> transformation related protein 53; targeted mutation 1.1, David G Johnson
Primary Identifier  MGI:4819616 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Trp53
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 4 was replaced with a modified human exon 4 in which nucleotide substitution created the proline variant of the p.R72P polymorphism (SNP rs1042522). A loxP site flanked neomycin resistance gene cassette inserted upstream of exon 2 was removed by Cre-mediated recombination.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • p53<P>,
  • Trp53<R72P>,
  • Trp53<R72P>,
  • p53<P>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





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