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Allele : Tg(Tnnt2-TNNT2*R92Q)M-2Ajm transgene insertion M-2, Ali J Marian

Primary Identifier  MGI:4819719 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Tnnt2-TNNT2*R92Q)M-2Ajm
Strain of Origin  C3H and C57BL/6 and ICR Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of a -497 bp fragment of the mouse Tnnt2 promoter driving expression of a full length human TNNT2 cDNA containing a G to A substitution that results in an Arg 92 Gln mutation. Five lines were generated (M-1, M-2, M-3, M-4. M-5). In this line (M-2) transgene transcript and protein make up 15% and 9%, respectively, of the total TNNT2 pool.
  • mutations:
  • Insertion
  • synonyms:
  • cTnT-Q92,
  • cTnT-Q92
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories