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Allele : Pcbp2<tm1(KOMP)Mbp> poly(rC) binding protein 2; targeted mutation 1, Mouse Biology Program, UC Davis

Primary Identifier  MGI:4820015 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Pcbp2
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
description  Germline transmission was made in mutant cell line DEPD00527_4_A05 (J:233719).
molecularNote  The insertion of the L1L2_Bact_P cassette created a deletion of size 1905 starting at position 102381333 and ending at position 102383238 of Chromosome 15 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories