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Allele : Tg(Fabp1-cre-GH1)1Jig transgene insertion 1, Jeffrey I Gordon

Primary Identifier  MGI:4820575 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(Fabp1-cre-GH1)1Jig
Strain of Origin  FVB/N Is Recombinase  true
Is Wild Type  false
molecularNote  A 1.0 kb fragment encoding cre recombinase was placed between nucleotides -596 to +21 of the rat Fabp1 and nucleotides +3 to +2150 of the human growth hormone gene (hGH; GH1). The purified fragment and injected into FVB/N oocytes. RNase protection assays in 8-week old mice demonstrated cre mRNA expression levels in small intestine (high in proximal half, lower in distal portion) and cecum (moderate) with barely detectable levels in the colon. Expression was also detected in the liver.
  • mutations:
  • Insertion
  • synonyms:
  • Fabpl<-596 to +21>Cre-hGH,
  • Fabpl<-596 to +21>Cre-hGH
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

2 Publication categories